منابع مشابه
Mathematical Modeling of Thrombus Growth Phenomenological Models
Phenomenological mathematical model of laser-induced thrombi growth is developed on the basis of Bogolubov’s hierarchy of time scales. The stochastic character of thrombi growth is revealed in the model by explicit introduction of the probability function. The main foundations of the model correspond to the basic experimental results concerning thrombus formation obtained in recent years. The m...
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Submitted for the DFD14 Meeting of The American Physical Society Mesoscopic Modeling of Thrombus Formation and Growth: Platelet Deposition in Complex Geometries ALIREZA YAZDANI, GEORGE KARNIADAKIS, Brown University — Haemodynamics and blood rheology are important contributing factors to thrombus formation at a vulnerable vessel wall, and adhesion of platelets to a vascular surface, particularly...
متن کاملThrombus formation reimagined.
In 1882, Dr Giulio Bizzozero described the use of intravital microscopy to detect the accumulation of platelets following needleinduced injury of the mesenteric artery in rabbits and guinea pigs. Bizzozero’s paper was not only the first to define the platelet in name (“Blutplättchen” in German) but was also the first to functionally define platelets as the primary cell type contributing to thro...
متن کاملMechanisms of thrombus formation.
N Engl J Med 2008;359:938-49. Copyright © 2008 Massachusetts Medical Society. Hemostasis is the process that maintains the integrity of a closed, high-pressure circulatory system after vascular damage. Vessel-wall injury and the extravasation of blood from the circulation rapidly initiate events in the vessel wall and in blood that seal the breach. Circulating platelets are recruited to the sit...
متن کاملPlatelet Thrombus Formation
severe homozygous von Willebrand factor (vWF)-deficient pigs (vWF<3%) (n=6), and heterozygous vWF-deficient pigs (vWF=24%) (n=2). Thrombus formation was measured by autologous "'In-platelet labeling and by ultrastructural morphology. Heparinized and native blood from these pigs was perfused over the substrate for 3 and 5 minutes at local shear rates from 212 to 3,380/sec. On collagen type I exp...
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ژورنال
عنوان ژورنال: Biotechnology and Bioengineering
سال: 2017
ISSN: 0006-3592,1097-0290
DOI: 10.1002/bit.26343